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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5J
All Species:
4.85
Human Site:
S272
Identified Species:
11.85
UniProt:
Q15735
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15735
NP_001002837.1
1006
107197
S272
S
P
P
C
I
Q
T
S
P
D
P
R
L
S
P
Chimpanzee
Pan troglodytes
A0FI79
644
70203
Rhesus Macaque
Macaca mulatta
XP_001110784
811
87406
P149
V
P
P
P
L
P
K
P
P
R
S
P
S
R
S
Dog
Lupus familis
XP_543486
1008
107177
P274
S
T
S
L
I
Q
S
P
P
D
P
R
I
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P59644
1003
107585
F273
S
P
P
R
A
Q
A
F
S
D
P
R
L
S
P
Rat
Rattus norvegicus
Q9JMC1
1001
107190
S273
S
P
P
R
A
Q
T
S
S
D
P
R
L
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507443
768
84124
F106
L
A
T
T
P
R
P
F
G
Q
L
A
P
P
P
Chicken
Gallus gallus
XP_415287
1011
110631
D284
C
P
G
T
A
A
E
D
G
A
F
R
I
T
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_698057
784
85922
S122
S
P
L
P
Y
C
N
S
Q
K
P
T
S
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780987
442
50512
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.8
78.9
87.5
N.A.
82.2
83.9
N.A.
56.2
42.2
N.A.
40.8
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
32.3
79.4
91.5
N.A.
86.7
88
N.A.
63.6
55.3
N.A.
51.1
N.A.
N.A.
N.A.
N.A.
29.3
P-Site Identity:
100
0
20
60
N.A.
66.6
80
N.A.
6.6
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
0
26.6
73.3
N.A.
66.6
80
N.A.
13.3
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
30
10
10
0
0
10
0
10
0
0
0
% A
% Cys:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
40
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
20
0
0
10
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
20
0
0
0
0
0
0
0
20
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% K
% Leu:
10
0
10
10
10
0
0
0
0
0
10
0
30
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
60
40
20
10
10
10
20
30
0
50
10
10
20
50
% P
% Gln:
0
0
0
0
0
40
0
0
10
10
0
0
0
0
0
% Q
% Arg:
0
0
0
20
0
10
0
0
0
10
0
50
0
10
0
% R
% Ser:
50
0
10
0
0
0
10
30
20
0
10
0
20
40
10
% S
% Thr:
0
10
10
20
0
0
20
0
0
0
0
10
0
10
10
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _